When used in the same manner as external rotating drives (hard drives, optical drives, or floppy drives), i.e. in ignorance of their technology, USB drives' failure is more likely to be sudden: while rotating drives can fail instantaneously, they more frequently give some indication (noises, slowness) that they are about to fail, often with enough advance warning that data can be removed before total failure. USB drives give little or no advance warning of failure. Furthermore, when internal wear-leveling is applied to prolong life of the flash drive, once failure of even part of the memory occurs it can be difficult or impossible to use the remainder of the drive, which differs from magnetic media, where bad sectors can be marked permanently not to be used.[74]
In the arcade game In the Groove and more commonly In The Groove 2, flash drives are used to transfer high scores, screenshots, dance edits, and combos throughout sessions. As of software revision 21 (R21), players can also store custom songs and play them on any machine on which this feature is enabled. While use of flash drives is common, the drive must be Linux compatible.
USB flash drives are often used for storage, data back-up and transfer of computer files. Compared with floppy disks or CDs, they are smaller, faster, have significantly more capacity, and are more durable due to a lack of moving parts. Additionally, they are immune to electromagnetic interference (unlike floppy disks), and are unharmed by surface scratches (unlike CDs). Until about 2005, most desktop and laptop computers were supplied with floppy disk drives in addition to USB ports, but floppy disk drives became obsolete after widespread adoption of USB ports and the larger USB drive capacity compared to the 1.44 MB 3.5-inch floppy disk.
Artists have sold or given away USB flash drives, with the first instance believed to be in 2004 when the German punk band Wizo released the Stick EP, only as a USB drive. In addition to five high-bitrate MP3s, it also included a video, pictures, lyrics, and guitar tablature.[58] Subsequently, artists including Nine Inch Nails and Kylie Minogue[59] have released music and promotional material on USB flash drives. The first USB album to be released in the UK was Kiss Does... Rave, a compilation album released by the Kiss Network in April 2007.[60]
Audio tape cassettes and high-capacity floppy disks (e.g., Imation SuperDisk), and other forms of drives with removable magnetic media, such as the Iomega Zip and Jaz drives, are now largely obsolete and rarely used. There are products in today's market that will emulate these legacy drives for both tape and disk (SCSI1/SCSI2, SASI, Magneto optic, Ricoh ZIP, Jaz, IBM3590/ Fujitsu 3490E and Bernoulli for example) in state-of-the-art Compact Flash storage devices – CF2SCSI.
Some file systems are designed to distribute usage over an entire memory device without concentrating usage on any part (e.g., for a directory) to prolong the life of simple flash memory devices. Some USB flash drives have this 'wear leveling' feature built into the software controller to prolong device life, while others do not, so it is not necessarily helpful to install one of these file systems.[39]
Flash drives may present a significant security challenge for some organizations. Their small size and ease of use allows unsupervised visitors or employees to store and smuggle out confidential data with little chance of detection. Both corporate and public computers are vulnerable to attackers connecting a flash drive to a free USB port and using malicious software such as keyboard loggers or packet sniffers.
The various writable and re-writable forms of CD and DVD are portable storage media supported by the vast majority of computers as of 2008. CD-R, DVD-R, and DVD+R can be written to only once, RW varieties up to about 1,000 erase/write cycles, while modern NAND-based flash drives often last for 500,000 or more erase/write cycles. DVD-RAM discs are the most suitable optical discs for data storage involving much rewriting.
Flash memory cards, e.g., Secure Digital cards, are available in various formats and capacities, and are used by many consumer devices. However, while virtually all PCs have USB ports, allowing the use of USB flash drives, memory card readers are not commonly supplied as standard equipment (particularly with desktop computers). Although inexpensive card readers are available that read many common formats, this results in two pieces of portable equipment (card plus reader) rather than one.
A recent development for the use of a USB Flash Drive as an application carrier is to carry the Computer Online Forensic Evidence Extractor (COFEE) application developed by Microsoft. COFEE is a set of applications designed to search for and extract digital evidence on computers confiscated from suspects.[48] Forensic software is required not to alter, in any way, the information stored on the computer being examined. Other forensic suites run from CD-ROM or DVD-ROM, but cannot store data on the media they are run from (although they can write to other attached devices, such as external drives or memory sticks).

"Nice device for bulky files....I have 2 of these flash drives and it's more convenient for me to store backups of my most important files on 2 of these flash drives than an external drive because it's easier for me to transfer my data files between 3 devices, carry the drive around in my pocket, and the transfers are easy and fast since it's USB 3.0"

The U3 company works with drive makers (parent company SanDisk as well as others) to deliver custom versions of applications designed for Microsoft Windows from a special flash drive; U3-compatible devices are designed to autoload a menu when plugged into a computer running Windows. Applications must be modified for the U3 platform not to leave any data on the host machine. U3 also provides a software framework for independent software vendors interested in their platform.
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