A recent development for the use of a USB Flash Drive as an application carrier is to carry the Computer Online Forensic Evidence Extractor (COFEE) application developed by Microsoft. COFEE is a set of applications designed to search for and extract digital evidence on computers confiscated from suspects.[48] Forensic software is required not to alter, in any way, the information stored on the computer being examined. Other forensic suites run from CD-ROM or DVD-ROM, but cannot store data on the media they are run from (although they can write to other attached devices, such as external drives or memory sticks).
Some manufacturers deploy physical authentication tokens in the form of a flash drive. These are used to control access to a sensitive system by containing encryption keys or, more commonly, communicating with security software on the target machine. The system is designed so the target machine will not operate except when the flash drive device is plugged into it. Some of these "PC lock" devices also function as normal flash drives when plugged into other machines.
The development of high-speed serial data interfaces such as USB made semiconductor memory systems with serially accessed storage viable, and the simultaneous development of small, high-speed, low-power microprocessor systems allowed this to be incorporated into extremely compact systems. Serial access requires far fewer electrical connections for the memory chips than does parallel access, which has simplified the manufacture of multi-gigabyte drives.
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Motherboard firmware (including BIOS and UEFI) can be updated using USB flash drives. Usually, new firmware image is downloaded and placed onto a FAT16- or FAT32-formatted USB flash drive connected to a system which is to be updated, and path to the new firmware image is selected within the update component of system's firmware.[49] Some motherboard manufacturers are also allowing such updates to be performed without the need for entering system's firmware update component, making it possible to easily recover systems with corrupted firmware.[50]
Most USB flash drives do not include a write protection mechanism. This feature, which gradually became less common, consists of a switch on the housing of the drive itself, that prevents the host computer from writing or modifying data on the drive. For example, write protection makes a device suitable for repairing virus-contaminated host computers without the risk of infecting a USB flash drive itself. In contrast to SD cards, write protection on USB flash drives (when available) is connected to the drive circuitry, and is handled by the drive itself instead of the host (on SD cards handling of the write-protection notch is optional).
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Flash memory cards, e.g., Secure Digital cards, are available in various formats and capacities, and are used by many consumer devices. However, while virtually all PCs have USB ports, allowing the use of USB flash drives, memory card readers are not commonly supplied as standard equipment (particularly with desktop computers). Although inexpensive card readers are available that read many common formats, this results in two pieces of portable equipment (card plus reader) rather than one.

In addition to providing reliable storage for information, many of these products come with security software that protects your personal data if you lose your device. The software secures files with 128-bit AES encryption and requires a password to unlock the stored information. It also features a drag-and-drop user interface that simplifies transferring and securing your data. 
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