USB flash drives use the USB mass storage device class standard, supported natively by modern operating systems such as Windows, Linux, macOS and other Unix-like systems, as well as many BIOS boot ROMs. USB drives with USB 2.0 support can store more data and transfer faster than much larger optical disc drives like CD-RW or DVD-RW drives and can be read by many other systems such as the Xbox One, PlayStation 4, DVD players, automobile entertainment systems, and in a number of handheld devices such as smartphones and tablet computers, though the electronically similar SD card is better suited for those devices.
Specially manufactured flash drives are available that have a tough rubber or metal casing designed to be waterproof and virtually "unbreakable". These flash drives retain their memory after being submerged in water, and even through a machine wash. Leaving such a flash drive out to dry completely before allowing current to run through it has been known to result in a working drive with no future problems. Channel Five's Gadget Show cooked one of these flash drives with propane, froze it with dry ice, submerged it in various acidic liquids, ran over it with a jeep and fired it against a wall with a mortar. A company specializing in recovering lost data from computer drives managed to recover all the data on the drive.[64] All data on the other removable storage devices tested, using optical or magnetic technologies, were destroyed.
Most USB-based flash technology integrates a printed circuit board with a metal tip, which is simply soldered on. As a result, the stress point is where the two pieces join. The quality control of some manufacturers does not ensure a proper solder temperature, further weakening the stress point.[77][78] Since many flash drives stick out from computers, they are likely to be bumped repeatedly and may break at the stress point. Most of the time, a break at the stress point tears the joint from the printed circuit board and results in permanent damage. However, some manufacturers produce discreet flash drives that do not stick out, and others use a solid metal uni-body that has no easily discernible stress point. SD cards serve as a good alternative to USB drives since they can be inserted flush.

There's a lot to choose from when it comes to buying a flash drive. The most important thing to consider is size. The whole point of a USB drive is to store lots of data in a small space, so think about what kinds of files you'll want to house on your flash drive. Movies and music take quite a bit of space, so if you're carrying your whole entertainment library with you, you'll want a big thumb drive – at least 16GB. Books and other text-based documents require relatively little storage space, so people like students and working professionals using Microsoft Office would be happy transferring Word documents or Excel files with as little as 1GB of space. On the other hand, if you are using photo or music editing software, you'll want a USB flash drive with lots of storage capacity to transfer graphic and music files.

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